ICASE is a joint venture between three of the top measurement science institutions in the world:
Purdue University, Indiana University and the University of Notre Dame.
Researchers at Indiana University report in a recent publication in Journal of the American Chemical Society that the trimeric spike protein of the SARS CoV-2 virus is differentially glycosylation. Using the technique of Charge Detection Mass Spectrometry pioneered at IU, Professors Martin Jarrold, David Clemmer and co-workers have revealed an unusual feature relating to glycosylation of the spike protein - a finding that simply would not be possible using conventional bottom-up proteomics studies.
Professor Rebecca Whelan and co-workers have reported recent findings in a cover article in The Analyst detailing isolation of a key biomarker for ovarian cancer, CA125, from ascites fluid. CA125 helps cancer evade the immune system and is a clinically significant biomarker of ovarian cancer. Read more
Check out this recent article from the American Institute for Chemical Engeineers (AIChE) journal highlighting collaborative research between the groups of Professor Merlin Bruening (Notre Dame) and Professor Jacqueline Linnes (Purdue) link. The research project, carried out under the auspices of the NSF Center for Bioanalytical Metrology has involved ongoing participation from a number of industry partners including Eli Lilly, Sartorius, Corteva Agriscience, Indiana Bioscience Research Institute and Bristol Myers Squibb